Key Key Papers Concerning Exposure to Environmental Chemicals

 

 
Studies

Studies are divided into the following categories:

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Reviews

Fontham ET, Thun MJ, Ward E, Portier KM, Balch AJ, Delancey JO, Samet JM; ACS Cancer and the Environment Subcommittee.  (2009) American Cancer Society perspectives on environmental factors and cancer. CA Cancer J Clin. 59(6):343-51.  Open Access; available from: http://caonline.amcancersoc.org/cgi/content/full/59/6/343

Diamanti-Kandarakis E, Bourguignon JP, Giudice LC, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC.  (2009) Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocr Rev. 30(4):293-342.

Crain DA, Janssen SJ, Edwards TM, Heindel J, Ho SM, Hunt P, Iguchi T, Juul A, McLachlan JA, Schwartz J, Skakkebaek N, Soto AM, Swan S, Walker C, Woodruff TK, Woodruff TJ, Giudice LC, Guillette LJ Jr. (2008) Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing. Fertil Steril. 90(4):911-40.

Grandjean P, Bellinger D, Bergman A, Cordier S, Davey-Smith G, Eskenazi B, Gee D, Gray K, Hanson M, van den Hazel P, Heindel JJ, Heinzow B, Hertz-Picciotto I, Hu H, Huang TT, Jensen TK, Landrigan PJ, McMillen IC, Murata K, Ritz B, Schoeters G, Skakkebaek NE, Skerfving S, Weihe P. (2008) The faroes statement: human health effects of developmental exposure to chemicals in our environment. Basic Clin Pharmacol Toxicol. 102(2):73-5.  Open Access; available from: http://www3.interscience.wiley.com/cgi-bin/fulltext/119425369/HTMLSTART

Filby AL, Neuparth T, Thorpe KL, Owen R, Galloway TS, Tyler CR. (2007) Health impacts of estrogens in the environment, considering complex mixture effects. Environ Health Perspect. 115(12):1704-10.  Free Full Text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137123/?tool=pubmed

Kortenkamp A. (2008) Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology. Int J Androl. 31(2):233-40.

Kortenkamp A, Faust M, Scholze M, Backhaus T. (2007) Low-level exposure to multiple chemicals: reason for human health concerns? Environ Health Perspect. 115 Suppl 1:106-14.  Open Access; available from: http://ehp.niehs.nih.gov/members/2007/9358/9358.pdf
Kortenkamp A. Ten years of mixing cocktails: a review of combination effects of endocrine-disrupting chemicals. (2007) Environ Health Perspect. 115 Suppl 1:98-105.  Open Access; available from: http://ehp.niehs.nih.gov/members/2007/9357/9357.pdf

Newby JA, Howard CV. (2005) Environmental Influences in Cancer Aetiology. J Nutri and Environ Med. 15(2/3): 56-114. Available for download. The purpose of this review is to inform both scientists and clinicians about the increase in cancer incidence throughout the Western World and to discuss environmental influences in cancer aetiology, in order to stimulate thoughts about plausible aetiological mechanisms and possible preventative measures.

Clapp RW, Howe GK, Jacobs MM. (2005) Environmental and Occupational Causes of Cancer: A Review of Recent Scientific Literature. This document is available at www.sustainableproduction.org and www.cheforhealth.org.

Sanborn M, Cole D, Kerr K, Vakil C, Sanin H, Bassil K. (2004) The Ontario College of Family Physicians: Pesticides Literature Review. Download here.

Sharpe RM. (2003) The 'oestrogen hypothesis' - where do we stand now? Int J Androl. 26:2-15.

Maffini MV, Rubin BS, Sonnenschein C, Soto AM. (2006) Endocrine disruptors and reproductive health: The case of bisphenol-A. Mol Cell Endocrinol. 254-255:179-86. Epub 2006 Jun 15.

Fenton SE. (2006) Endocrine-disrupting compounds and mammary gland development: early exposure and later life consequences. Endocrinology. 147(6 Suppl):S18-24. Epub 2006 May 11.

Newbold RR, Padilla-Banks E, Jefferson WN. (2006) Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations. Endocrinology. 47(6 Suppl):S11-7. Epub 2006 May 11.

Clapp RW, Howe GK, Jacobs MM. (2007) Environmental and occupational causes of cancer: A call to act on what we know. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 631-639.

Belpomme D. (2007) Cancer and the environment: Facts, figures, methods and misinterpretations. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 611-613.

Davis DL, Donovan M, Herberman R, Gaynor M, Axelrod D, van Larebeke N, Sasco AJ. (2007) The need to develop centers for environmental oncology. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 614-622.

Irigaray P, Newby JA, Clapp R, Hardell L, Howard V, Montagnier L, Epstein S, Belpomme D. (2007) Lifestyle-related factors and environmental agents causing cancer: An overview. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 640-658.

Irigaray P, Newby JA, Lacomme S, Belpomme D. (2007) Overweight/obesity and cancer genesis: More than a biological link. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment).  61, 665-678.

Belpomme D, Irigaray P, Hardell L, Clapp R, Montagniere L, Epstein S, Sasco A-J. (2007) The multitude and diversity of environmental carcinogens. Environmental Research. 10(3), 414-429.

 Belpomme  D, Irigaray P, Sasco AJ , Newby JA, Howard V, Clapp R, Hardell, L. (2007) The growing incidence of cancer: Role of lifestyle and screening detection (Review).  Int J Oncol. 30 (5):1037-49.  

Annie J. Sasco, (2007) Cancer and globalization. Biomedicine & Pharmacotherapydoi:10.1016/j.biopha.2007.10.015 (article in Press).

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Epidemiology

Melzer D, Rice NE, Lewis C, Henley WE, Galloway TS (2010) Association of Urinary Bisphenol A Concentration with Heart Disease: Evidence from NHANES 2003/06. PLoS ONE 5(1): e8673. doi:10.1371/journal.pone.0008673  Open Access; available from: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0008673

Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, et al. (2008) Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults.  Journal of the American Medical Association, 300: 1303–1310.

 

Newby JA, Busby CC, Howard CV, Platt MJ. (2007) The cancer incidence temporality index: An index to show temporal changes in the age of onset of overall and specific cancer (England and Wales, 1971–1999). Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 623-630.

Sung T-I, Chen P-C, Jyuhn-Hsiarn Lee L, Lin Y-P, Hsieh G-Y, Wang J-D. (2007) Increased standardized incidence ratio of breast cancer in female electronics workers. BMC Public Health. 7:102 doi:10.1186/1471-2458-7-102.

Merhi M, Raynal H, Cahuzac E, Vinson F, Cravedi JP, Gamet-Payrastre L. (2007) Occupational exposure to pesticides and risk of hematopoietic cancers: meta-analysis of case–control studies. Cancer Causes Control. 8, 1209–1226.

Bouchardy C, Fioretta G, Verkooijen HM, Vlastos G, Schaefer P, Delaloye J-F, Neyroud-Caspar I, Balmer Majno S, Wespi Y, Forni M, Chappuis P, Sappino A-P, Rapiti E. (2007) Recent increase of breast cancer incidence among women under the age of forty. British Journal of Cancer. 96, 1743 – 1746.

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Cancer is an Environmental Disease

Lichtenstein P, Holm NV, Vrkasalo PK. (2000) Environmental and heritable factors in the causation of cancer. N Engl J Med. 342:78-85.

Czene K, Lichtenstein P, Hemminki K. (2002) Environmental and heritable causes of cancer among 9.6 million individuals in the Swedish Family-Cancer Database. Int J Cancer. 99:260-266.

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Specific Cancer Sites: Prostate

Potti A, Panwalkar AW, Langness E. (2003) Prevalence of pesticide exposure in young males (,/5 50 years) with adenocarcinoma of the prostate. J Carcinog. 2:4.

Jaga K, Dharmani C. (2005) The epidemiology of pesticide exposure and cancer: A review. Rev Environ Health. 20(1):15-38.

Settimi L, Masina A, Andrion A, Axelson O. (2003) Prostate cancer and exposure to pesticides in agricultural settings. Int J Cancer. 104(4):458-61.

Ritchie JM, Vial SL, Fuortes LJ, Guo H, Reedy VE, Smith EM. (2003) Organochlorines and risk of prostate cancer. J Occup Environ Med. 45(7):692-702.

Hardell L, Andersson S-O Carlberg M, Bohr L, van Bavel B, Lindstrom G, Bjornfoth H, Ginman C. (2006) Adipose Tissue Concentrations of Persistent Organic Pollutants and the Risk of Prostate Cancer. J Occup Environ Med. 48(7):700-707.

Prins GS, Birch L, Tang W-Y, Hob S-M. (2007) Developmental estrogen exposures predispose to prostate carcinogenesis with aging. Reproductive Toxicology. 23, 374–382.

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Specific Cancer Sites: Breast

Brody JG, Moysich KB, Humblet O, Attfield KR, Beehler GP, Rudel RA. (2007) Environmental Pollutants and Breast Cancer. Supplement to Cancer (Environmental Factors in Breast Cancer). (109):12, 2667-2711.

Rudel RA, Attfield KR. Schifano JN, Brody JG. (2007) Chemicals Causing Mammary Gland Tumors inAnimals Signal New Directions for Epidemiology, Chemicals Testing, and Risk Assessment for Breast Cancer Prevention. Supplement to Cancer (Environmental Factors in Breast Cancer). (109):12, 2365-2666.

Brody JG, Rudel RA. (2008) Environmental Pollutants and Breast Cancer: The Evidence from Animal and Human Studies. Breast Diseases: A Year book Quarterly. (19):1, 17-19.

Sasco AJ. (2003) Breast cancer and the environment. Horm Res. 60:50

Palmer JR, Wise LA, Hatch EE, Troisi R, Titus-Ernstoff L, Strohsnitter W, Kaufman R, Herbst AL, Noller KL, Hyer M, Hoover RN. (2006) Prenatal Diethylstilbestrol Exposure and Risk of Breast Cancer. Cancer Epidemiol Biomark Prev. 15:1509-1514.

Darbre PD. (2006) Environmental oestrogens, cosmetics and breast cancer. Best Pract & Res Clin Endocrinol & Metabol. 20(1):121-143.

Ibarluzea Jm J, Fernandez MF, Santa-Marina L, Olea-Serrano MF, Rivas AM, Aurrekoetxea JJ, Exposito J, Lorenzo M, Torne P, Villalobos M, Pedraza V, Sasco AJ, Olea N. (2004) Breast cancer risk and the combined effect of environmental estrogens. Cancer Causes Control. 15(6):591-600.

Kortenkamp A. (2006) Breast cancer, oestrogens and environmental pollutants: a re-evaluation from a mixture perspective. Int J Androl. 29(1):193-8.

Markey CM, Luque EH, Munoz de Toro M. (2001) In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland. Biol Reprod. 65:1215-1223.

Cassidy RA, Natarajan S, Vaughan GM. (2005) The link between the insecticide heptachlor epoxide, estradiol, and breast cancer. Breast Cancer Res Treat. 90(1):55-64.

Murray TJ, Maffini MV, Ucci AA, Sonnenschein C, Soto AM. (2007) Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure. Reproductive Toxicology. 23, 383–390.

Jenkins S, Rowell C, Wang J, Lamartiniere CA. (2007) Prenatal TCDD exposure predisposes for mammary cancer in rats. Reproductive Toxicology. 23, 391–396.

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Specific Cancer Sites: Testes

Bay K, Asklund C, Skakkebaek NE, Andersson A-M. (2006) Testicular dysgenesis syndrome: possible role of endocrine disrupters. Best Pract & Res Clin Endocrinol & Metabol. (20)1:77-90. (doi:10.1016/j.beem.2005.09.004, available online at Science Direct.

Hardell L, Van Bavel B, Lindstrom G, Carlberg M, Eriksson M, Dreifaldt AC, Wijkstrom H, Starkhammar H, Hallquist A, Kolmert T. (2004) Concentrations of polychlorinated biphenyls in blood and the risk for testicular cancer. Int J Androl. 27(5):282-90.

Hardell L, van Bavel B, Lindstrom G, Carlberg M, Dreifaldt AC, Wijkstrom H, Starkhammar H, Eriksson M, Hallquist A, Kolmert T. (2003) Increased concentrations of polychlorinated biphenyls, hexachlorobenzene, and chlordanes in mothers of men with testicular cancer. Environ Health Perspect. 111(7):930-4.

Hardell L, Malmqvist N, ran Ohlson CG, Westberg H, Eriksson M. (2004) Testicular cancer and occupational exposure to polyvinyl chloride plastics: a case-control study. Int J Cancer 109:425-429.

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Specific Cancer Sites: Non-Hodgkin's Lymphoma

De Roos AJ, Hartge P, Lubin JH, Colt JS, Davis S, Cerhan JR, Severson RK, Cozen W, Patterson DG Jr, Needham LL, Rothman N. (2005) Persistent organochlorine chemicals in plasma and risk of non-Hodgkin's lymphoma. Cancer Res. 65(23):11214-26.

Buckley JD, Meadows AT, Kadin ME, Le Beau MM, Siegel S, Robison LL. (2000) Pesticide exposures in children with non-Hodgkin lymphoma. Cancer. 89(11):2315-21.

Fritschi L, Benke G, Hughes AM, Kricker A, Turner J, Vajdic CM, Grulich A, Milliken S, Kaldor J, Armstrong BK. (2005) Occupational exposure to pesticides and risk of non-Hodgkin's lymphoma. Am J Epidemiol. 162(9):849-57.

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Occupational and Inadvertent Exposure to Carcinogens

Zheng T, Zahm SH, Cantor KP, Weisenburger DD, Zhang Y, Blair A. (2001) Agricultural exposure to carbamate pesticides and risk of non-Hodgkin lymphoma. J Occup Environ Med. 43(7):641-9.

Gago-Dominguez M, Bell D, Watson M, Yuan JM, Castelao JE, Hein DW, Chan KK, Coetzee GA, Ross RK, Yu MC.(2003) Permanent hair dyes and bladder cancer: risk modification by cytochrome P4501A2 and N-acetyltransferases 1 and 2. Carcinogenesis 24:483-489.

IARC.(1993) Occupational exposures of hairdressers and barbers and personal use of hair colourants; some hair dyes, cosmetic colourants, industrial dyestuffs and aromatic amines. IARC monographs on the evaluation of the carcinogenic risks of chemicals to humans, Vol. 57. Lyon: IARC Press; 1993.

Schettler T, (2003) Human exposure to phthalates via consumer products. Int J Androl. 29:134-139.

Zumbado M, Goethals M, Alvarez-Leon EE, Luzardo OP, Cabrera F, Serra-Majem L, Dominguez-Boada L. (2005) Inadvertent exposure to organochlorine pesticides DDT and derivatives in people from the Canary Islands (Spain). Sci Total Environ. 339(1-3):49-62.

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Toxicological Evidence for Low Dose Effects (Environmentally Relevant Doses)

Melnick R, Lucier G, Wolfe M, Hall R, Stancel G, Prins G, Gallo M, Reuhl K, Ho S-M, Brown T. (2002) Summary of the National Toxicology Program's report of the endocrine disruptors low-dose peer review. Environ Health Perspect. 110:427-431.

vom Saal FS, Hughes C, (2005) An Extensive New Literature Concerning Low-Dose Effects of Bisphenol A Shows the Need for a New Risk Assessment. Environ Health Perspect 113:926-933. doi:10.1289/ehp.7713 Available on-line.

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Pre, Peri and Post-Natal Exposure and Subsequent Cancer Risk

Schecter A, Ryan JJ, Papke O. Decrease in levels and body burden of dioxins, dibenzofurans, PCBs, DDE, and HCB in blood and milk in a mother nursing twins over a thirty-eight month period. Chemosphere. 37:1807-1816.

Ma X, Buffler PA, Gunier RB, Dahl G, Smith MT, Reinier K, Reynolds P. (2002) Critical windows of exposure to household pesticides and risk of childhood leukemia. Environ Health Perspect. 110:955-960.

Brown NM, Manzolillo PA, Zhang J-X, Wang J, lamartinere CA. (1998) Prenatal TCDD and predisposition to mammary cancer in the rat. Carcinogenesis. 19:1623-1629.

Fenton SE, Hamm JT, Birnbaum LS, Youngblood GL. (2002) Persistent abnormalities in the rat mammary gland following gestational and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicol Sci. 67:63-74.

Markey CM, Luque EH, Munoz de Toro M. (2001) In utero exposure to bisphenol A alters the development and tissue organization of the mouse mammary gland. Biol Reprod. 65:1215-1223.

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Childhood

Hoffmann W,Terschueren C, Richardson DB. (2007)  Childhood Leukemia in the Vicinity of the Geesthacht Nuclear Establishments near Hamburg, Germany. Environ Health Perspect. 115, 947–952.

von Rettberg H, Hannman T, Subotic U, Brade J, Schaible T, Waag KL, Loff S. (2009) Use of di(2-ethylhexyl)phthalate-containing infusion systems increases the risk for cholestasis. Pediatrics. 124(2):710-6.

Other sites

Hardell L, Carlberg M, Hardell K, Björnfoth H, Wickbom G, Ionescu M, van Bavel B, Lindström G. (2007) Decreased survival in pancreatic cancer patients with high concentrations of organochlorines in adipose tissue. Biomedicine & Pharmacotherapy (Dossier : Cancer : Influence of environment). 61, 659-664.

 

 

 

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